Clofranil 25 mg
Clomipramine Hydrochloride
Category: Tablet
Manufacturer: Sun Pharmaceutical Ltd.
Price: 635.0 ৳
100's pack
10's Strip
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Related Medicines
Clomipramine Hydrochloride is used to treat depression, obsessions and phobias (irrational fears). It is also used to treat muscular weakness (cataplexy) associated with repeat attacks of extreme sleepiness (narcolepsy) in adults.
Tricyclic & related anti-depressant drugs
Clomipramine hydrochloride belongs to a group of medicines called "tricyclic antidepressants". This is thought to work either by increasing the amount of chemical "messengers" in the brain or by making their effects last longer. Clomipramine is a potent inhibitor of serotonin re-uptake in the brain. Significant antagonism at cholinergic and α1-receptors. Weak antagonism at dopamine receptors. It has also antidepressant, sedative and anticholinergic effects.
In particular, do not take this if you are taking the following: medicines for depression called monoamine oxidase inhibitors (MAOIs), or have taken them within the last 3 weeks.
Known hypersensitivity to clomipramine and any of the excipients in the tablets.
Cross-hypersensitivity to tricyclic antidepressants of the dibenzazepine group.
Concomitant use with a monoamine oxidase (MAO) inhibitor, or within 14 days before or after treatment with an irreversible MAO inhibitor, or within 14 days before moclobemide, a reversible MAO inhibitor.
Acute and recovery stages of myocardial infarction.
Congenital long QT syndrome.
Very common side effects are increase in appetite and weight gain, headaches, dizziness, nausea, constipation, dry mouth, increased sweating, shaking hands, tremor, difficulty in passing urine, problems with their eyes, feeling tired or sleepy, sexual disturbances, restlessness.
Pregnancy category C. As clomipramine passes into human milk, babies should be weaned or clomipramine gradually withdrawn.
Check with your doctor or pharmacist before taking your medicine if:
you have epilepsy (fits)
you have an overactive thyroid gland
you have a tumour (cancer) of the adrenal gland (such as phaeochromocytoma or neuroblastoma)
you have low blood pressure
you wear contact lenses
you have had severe constipation for a long time
you find yourself thinking about suicide
you have had a head injury and suffered brain damage
you are going to have ECT (electroconvulsive therapy)
you have an irregular heart beat or other problems with your heart
you have been diagnosed as having a low level of potassium in your blood (hypokalemia)
you have schizophrenia or any other mental disorder
you are elderly
you have glaucoma(increased pressure in the eye)
you have liver or kidney disease
you have any blood disorder
you have difficulties in passing urine (e.g. due to diseases of the prostate)
Keep out of the reach and sight of children. The capsules should be protected from heat and moisture.
Tricyclic & related anti-depressant drugs
Clomipramine hydrochloride belongs to a group of medicines called "tricyclic antidepressants". This is thought to work either by increasing the amount of chemical "messengers" in the brain or by making their effects last longer. Clomipramine is a potent inhibitor of serotonin re-uptake in the brain. Significant antagonism at cholinergic and α1-receptors. Weak antagonism at dopamine receptors. It has also antidepressant, sedative and anticholinergic effects.
Pregnancy category C. As clomipramine passes into human milk, babies should be weaned or clomipramine gradually withdrawn.
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