Biofol Kidz 50 mg/100 ml

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Generic: Folic acid

Category: Syrup

Manufacturer: Incepta Pharmaceuticals Ltd.

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Indications

Anemia, Nutritional supplement, Folic acid deficiency, Megaloblastic anemia, Neural tube defect This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. Folic Acid is contraindicated in untreated cobalamine deficiency.

Therapeutic Class

Drugs for Megaloblastic Anemia, Vitamin-B preparations

Pharmacology

Folic acid is essential for the production of certain coenzymes in many metabolic systems such as purine and pyrimidine synthesis. It is also essential in the synthesis and maintenance of nucleoprotein in erythropoesis. It also promotes WBC and platelet production in folate-deficiency anaemia.

Dosage and Administration

Administration: May be taken with or without food. Adult Dose: Oral Folate-deficient megaloblastic anaemia Adult: 5 mg daily for 4 mth, up to 15 mg daily in malabsorption states. Continued dosing at 5 mg every 1-7 days may be needed in chronic haemolytic states, depending on the diet and rate of haemolysis. Prophylaxis of megaloblastic anaemia in pregnancy Adult: 0.2-0.5 mg daily. Prophylaxis of neural tube defect in pregnancy Adult: 4 or 5 mg daily starting before pregnancy and continued through the 1st trimester. As supplement for women of child-bearing potential Adult: 0.4 mg daily. Child Dose: Folic Acid Deficiency Infants: 15 mcg/kg/day or 50 mcg/day 1-10 years: 1 mg/day initially, then 0.1-0.4 mg/day

Interaction

Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations.

Contraindications

This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. Folic Acid is contraindicated in untreated cobalamine deficiency.

Side Effects

Bronchospasm,Erythema,Malaise,Pruritus,Rash,Slight flushing

Pregnancy And Lactation

Pregnancy Category A. Adequate and well-controlled human studies have not shown any risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

Precautions And Warnings

Precaution: Treatment resistance may occur in patients with depressed haematopoiesis, alcoholism, deficiencies of other vitamins. Neonates. Lactation: Drug enters breast milk; safe for nursing

Storage Conditions

Store below 30°C in a dry place, away from light. Keep out of the reach of children.

Drug Classes

Drugs for Megaloblastic Anemia, Vitamin-B preparations

Mode of Action

Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy.

Pregnancy Category

Pregnancy category: A Lactation: Drug enters breast milk; safe for nursing

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Biofol Kidz 50 mg/100 ml

Indications

Therapeutic Class

Pharmacology

Dosage and Administration

Interaction

Contraindications

Side Effects

Pregnancy And Lactation

Precautions And Warnings

Storage Conditions

Drug Classes

Mode of Action

Pregnancy Category

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