Indications
Apirent is indicated for the treatment of excessive perspiration of the underarms, hands, feet and scalp.
Therapeutic Class
Miscellaneous topical agents
Pharmacology
Aluminium Chloride Hexahydrate acts locally in the stratum corneum and terminal duct to relieve hyperhidrosis. Aluminium salts cause an obstruction of the ducts of sweat glands at the skin surface. It seems that the metal (Aluminium) ions precipitate with mucopolysaccharides, damaging epithelial cells along with the duct lumen and forms a plug (gel) that blocks sweat output.
Dosage and Administration
Step 1: Apply Aluminium Chloride Hexahydrate topical solution at night after drying the affected areas carefully.Step 2: Wash off in the morning. Do not re-apply the product during the day.Step 3: Initially the product may be applied every night until sweating stops during the day. The frequency of application may be reduced to twice a week or less, if excess sweating is stopped during the day.
Interaction
There are no known drug interactions for Aluminium Chloride Hexahydrate topical solution.
Contraindications
Aluminium Chloride Hexahydrate is contraindicated in patients with known hypersensitivity to any of its components.
Side Effects
Aluminium Chloride Hexahydrate is normally well tolerated and adverse effects are only mild and short-lasting. But sometimes irritation of the skin like- stinging, burning, redness, swelling, tingling or itching of treated skin areas may occur. These irritations may be alleviated by use of a weak corticosteroid cream.
Pregnancy And Lactation
There are no restrictions on the use of this medication during pregnancy and lactation.
Precautions And Warnings
For external use only. Do not apply this medication to broken, irritated or recently shaved skin. Avoid contact with eyes, mouth, nose and lips. Avoid direct contact with clothing and polished metal or jewellery surfaces. Keep out of reach of children.
Storage Conditions
Store in a cool & dry place, protected from light. Keep out of reach of children. Keep away from naked flame. Store upright.
Drug Classes
Miscellaneous topical agents
Mode of Action
Aluminium Chloride Hexahydrate acts locally in the stratum corneum and terminal duct to relieve hyperhidrosis. Aluminium salts cause an obstruction of the ducts of sweat glands at the skin surface. It seems that the metal (Aluminium) ions precipitate with mucopolysaccharides, damaging epithelial cells along with the duct lumen and forms a plug (gel) that blocks sweat output.
Pregnancy Category
There are no restrictions on the use of this medication during pregnancy and lactation.
