Plan A 0.8%+1%+0.4% Vaginal Gel

    Plan A 0.8%+1%+0.4%

    Lactic acid + Citric acid + Potassium bitartrate vaginal

    Category: Vaginal Gel

    Manufacturer: Square Pharmaceuticals Ltd.

    Price: 120.0

    2 tubes(5 gm each)

    This Gel is used for: Contraception, To prevent pregnancy
    Adult Dose Contraception Indicated for prevention of pregnancy in females of reproductive potential for use as an on-demand contraceptive method Apply 1 prefilled applicator (5 grams) vaginally immediately before or up to 1 hr before each act of vaginal intercourse If >1 act of vaginal intercourse occurs within 1 hr, an additional dose must be applied
    Should be avoided in women who have had recurrent urinary tract infections or abnormalities or are using a vaginal ring.
    Side effects of Lactic acid + Citric acid + Potassium bitartrate vaginal : >10% Vulvovaginal burning sensation (18%) Vulvovaginal pruritus (14.5%) 1-10% Local discomfort in male partners (9.8%) Vulvovaginal mycotic infection (9.1%) Urinary tract infection (UTI) (9%) Vulvovaginal discomfort (9%) Bacterial vaginosis (8.4%) Vaginal discharge (5.5%) Genital discomfort (4.1%) Dysuria (3.1%) Vulvovaginal pain (2.1%)
    Pregnancy Do not use during pregnancy Discontinue during pregnancy No data available with the use in pregnant females or animals Lactation No data available on the presence of lactic acid, citric acid, and potassium bitartrate or their metabolites in human milk, or effects on breastfeeding or milk production
    Cystitis and pyelonephritis Cystitis, pyelonephritis, or other upper UTI may occur Avoid use of in females of reproductive potential with a history of recurrent UTI or urinary tract abnormalities
    Vaginal pH range is 3.5-4.5 and semen pH range is 7.2-8 Introduction of semen into the vagina causes increased pH (>6) owing to ejaculate alkalinity; the alkaline pH neutralizes the normally acidic vaginal environment allowing spermatozoa survival Vaginal pH lowering effect of lactic acid/citric acid/potassium bitartrate causes reduced sperm motility and contributes to intravaginal contraceptive activity
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