Tinobac 2 gm
Spectinomycin
Category: Injection
Manufacturer: Incepta Pharmaceuticals Ltd.
Allopathic
MFG. Licence No. Biological
193
MFG. Licence No. Non-Biological
108
Address
Zirabo, Savar, Dhaka Dewan Idris Road, Bara Rangamatia
Price: 225.0 ৳
2gm Vial
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Gonorrhoea, Acute gonorrheal urethritis, Cervicitis and proctitis
Hypersensitivity.
Adult Dose:
Intramuscular
Gonorrhoea
Adult: 2 g as a single dose. In cases whereby antibiotic resistance is prevalent, 4 g (10 mL) may be given but divided as two 5 mL inj, admin to 2 different inj sites.
Child Dose:
Intramuscular
Gonorrhoea
Child: Beyond newborn period and <45 kg: 40 mg/kg as a single dose. Max: 2 g.
May result in lithium toxicity when used concurrently. May increase or prolong the neuromuscular blocking effect of atracurium.
Hypersensitivity.
Nausea, dizziness, fever and chills, insomnia, urticaria, mild to moderate pain after IM inj, alterations in kidney and liver function, decrease in Hb and haematocrit.
Potentially Fatal: Anaphylaxis.
Precaution:
Ineffective in the treatment of syphilis and may mask or delay symptoms of incubating syphilis. Pregnancy and lactation. Monitoring Parameters Perform serologic test for syphilis at the time of gonorrhoea diagnosis and 3 mth later.
Information on overdosage in humans is not available. Hemodialysis has been reported to aid in the removal of intravenously administered Spectinomycin from the body.
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Macrolides
Spectinomycin binds to 30S subunit of the bacterial ribosome, thus inhibiting protein synthesis. It has modest activity against a wide range of gm+ve and gm-ve organisms, though anaerobic organisms are mostly resistant.
Pregnancy Category B. Since there are no controlled studies of Spectinomycin in pregnant women, and because animal reproduction studies are not always predictive of human responses, Spectinomycin should be used during pregnancy only if clearly needed. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Spectinomycin is administered to a nursing woman.
Samm Care