Uses of Tervent: - Asthma - Chronic obstructive pulmonary disease (COPD) Acute bronchospasm Hypersensitivity to sympathomimetics. Any condition of mother or foetus in which prolongation of pregnancy is dangerous.

How to use Terbutaline Sulphate: Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Terbutaline Sulphate may be taken with or without food, but it is better to take it at a fixed time. Administration: May be taken with or without food. Adult Dose: Oral Acute bronchospasm Adult: Initiate at 2.5 mg three/four times daily Maintenance: 5 mg three times daily q6hr while patient is awake; reduce dose to 2.5 mg q6hr Not to exceed 15 mg/Day Child Dose: Oral Acute bronchospasm Child: <12 years: 0.05 mg/kg three times daily initially; increase PRN, not to exceed 5 mg/day 12-15 years: 2.5 mg PO q6hr 3 times daily; not to exceed 7.5 mg/day >15 years: 5 mg/dose PO q8hr three times daily; reduce dose to 2.5 mg q6hr; not to exceed 15 mg/24hr Renal Dose: Renal Impairment GFR <50 mL/min: reduce dose by 50% GFR >50mL/min: Dose adjustment not necessary

Antagonised effects of beta-blockers. Increased risk of hypokaelemia with xanthine derivatives, corticosteriods and diuretics; increased risk of arrhythmias with inhaled anaesthetics, sympathomimetics.

Hypersensitivity to sympathomimetics. Any condition of mother or foetus in which prolongation of pregnancy is dangerous.

Common - Headache - Palpitations - Muscle weakness - Decreased potassium level in blood - Trembling Tachycardia, nervousness, tremor, palpitations, dizziness, headache, nausea, vomiting, anxiety, restlessness, lethargy, drowsiness, weakness, flushes, sweating, chest discomfort, muscle cramps, tinnitus. Rarely, seizures, hypersensitivity vasculitis, elevated liver enzymes. Potentially Fatal: Increased heart rate, transient hyperglycaemia, hypokalaemia, cardiac arrhythmias, pulmonary oedema, myocardial ischaemia.

Precaution: Patient w/ thyrotoxicosis, HTN, DM, ketoacidosis, CV disorders (e.g. ischaemic heart disease), convulsive disorders, coronary insufficiency or associated arrhythmias. Childn. Pregnancy and lactation. Monitoring Parameters Monitor cardiorespiratory function, serum K and glucose levels; Lactation: Distributed into breast milk, but in amounts generally considered insufficient to affect nursing infants (AAP Committee states compatible with nursing)

Terbutaline is a direct-acting sympathomimetic which relaxes bronchial smooth muscle by selective action on beta2 receptors. It also decreases uterine contractility.