Targocid 400 mg/vial
Teicoplanin
Category: IM/IV Injection
Manufacturer: Synovia Pharma PLC
Price: 1568.62 ৳
400 mg vial
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Teicoplanin is indicated in adults and in children of the following infections-
Complicated skin and soft tissue infections
Bone and joint infections
Hospital-acquired pneumonia
Community-acquired pneumonia
Complicated urinary tract infections
Infective endocarditis ... Read moreTeicoplanin is indicated in adults and in children of the following infections-
Complicated skin and soft tissue infections
Bone and joint infections
Hospital-acquired pneumonia
Community-acquired pneumonia
Complicated urinary tract infections
Infective endocarditis
Targocid is also indicated as an alternative oral treatment for Clostridium difficile infection-associated diarrhoea and colitis. Where appropriate, Teicoplanin should be administered in combination with other antibacterial agents.
Glycopeptide
Teicoplanin is a glycopeptide antibiotic that has shown in vitro bactericidal activity against both anaerobic and aerobic gram-positive organisms. Teicoplanin inhibits the growth of susceptible organisms by interfering with cell-wall biosynthesis at a site different from that affected by beta-lactams. It is active against staphylococci (including those resistant to methicillin and other beta-lactam antibiotics), streptococci, enterococci, Listeria monocytogenes, micrococci, group JK corynebacteria and gram-positive anaerobes including Clostridium difficile and peptococci.
Due to potential for increased adverse effects, Teicoplanin should be administered with caution in patients receiving concurrent nephrotoxic or ototoxic drugs, such as Aminoglycosides, Amphotericin B, Cyclosporion and Frusemide.
Teicoplanin is contraindicated in patients with known Hypersensitivity to the drug.
Local reaction: Erythema, injection site abscess when given intramuscularly.Allergic reaction: Rash, pruritus, fever, shivering, anaphylactic reactions.Gastrointestinal reactions: Nausea, vomiting, diarrhea.CNS reactions: Physical weakness, dizziness, headache.Hearing reactions: Ringing in the ears, balance disorders.
There are no adequate and well-controlled studies in pregnant women about administration of Teicoplanin; this drug should be used during pregnancy only if clearly needed. Information about the excretion of Teicoplanin in milk is not known.
Teicoplanin should be administered with caution in patients known to be hypersensitive to Vancomycin since cross-hypersensitivity may occur.
Store at a temperature not exceeding 30°C in a dry place. Protect from light. The reconstituted solution should be used immediately, or stored under refrigeration (2 to 8° C) for 24 hours maximum.
Glycopeptide
Teicoplanin is a glycopeptide-antibiotic produced by Actinoplanes teichomyceticus. It is presented as a sterile, pyrogen-free ivory white powder for reconstitution with water for injection. It is freely soluble in water and on reconstitution gives a clear solution. Teicoplanin inhibits the growth of susceptible organisms by interfering with cell-wall biosynthesis at a site different from that affected by beta-lactams. Peptidoglycan synthesis is blocked by specific binding to D-alanyl-D-alanine residues.
Pregnancy Category B3. Teicoplanin should not be used during confirmed or presumed pregnancy or during lactation unless the potential benefits outweigh possible risks.
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