Spiracin 1.5 MIU Tablet

    Spiracin 1.5 MIU

    Spiramycine

    Category: Tablet

    Manufacturer: Drug International Ltd.

    Uses of Spiracin: - Toxoplasmosis during pregnancy Susceptible infections, Cryptosporidiosis, Toxoplasmosis, Protozoal infections Hypersensitivity.
    How to use Spiramycine: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Spiramycine is to be taken empty stomach. Administration: May be taken with or without food. Adult Dose: Oral Toxoplasmosis; Protozoal infections; Cryptosporidiosis; Susceptible infections Adult: 6-9 million units/day in 2-3 divided doses, increased to 15 million units/day, given in divided doses for severe infections. Child Dose: Oral Child and Neonates: Chemoprophylaxis of congenital toxoplasmosis: 50 mg/kg bid.
    Decreases carbidopa absorption and levodopa concentrations. Increased risk of ventricular arrhythmias when used with astemizole, cisapride and terfenadine. Risk of acute dystonia when used with fluphenazine.
    Hypersensitivity.
    Common - Nausea - Vomiting - Abdominal pain - Diarrhea - Allergy Nausea, vomiting, abdominal pain, diarrhoea; urticaria, pruritus, macular rashes. Transient paraesthesia may occur. Potentially Fatal: Pseudomembranous colitis; anaphylaxis; neuromuscular blockade; ventricular arrhythmias, prolongation of QT interval.
    Precaution: Hepatic impairment; pregnancy and lactation. Monitor liver function. History of arrhythmias or predisposition to QT interval prolongation.
    Spiramycin is a macrolide antibacterial that inhibits protein synthesis by irreversibly binding to the 50S subunit of the ribosomal subunit thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth
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