Santinal MR 200 200 mg
Dipyridamole
Category: M R Capsule
Manufacturer: Unimed Unihealth Pharmaceuticals Ltd.
Unimed Unihealth Pharmaceuticals Ltd.
Allopathic
MFG. Licence No. Biological
219
MFG. Licence No. Non-Biological
121
Address
Bishaya Kuri Bari, Gazipur
Price: 9.0 ৳
Capsule
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Related Medicines
Uses of Santinal MR 200:
- Stroke
Stroke, Thromboembolism, Transient ischaemic attack
Hypersensitivity. Peptic ulcer.
Anti-platelet drugs
Dipyridamole causes an accumulation of adenosine, adenine nucleotides and cAMP by inhibiting the activity of adenosine deaminase and phosphodiesterase thus inhibiting platelet aggregation and may cause vasodilation.
How to use
Dipyridamole:
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use.
Dipyridamole is to be taken empty stomach.
Administration:
Should be taken on an empty stomach. Take on an empty stomach 1 hr before meals. May be taken w/ meals to reduce GI discomfort.
Adult Dose:
Oral
Thromboembolism Prophylaxis Post-Cardiac Valve Replacement
Adult: 75-100 mg PO q6hr as adjunct to warfarin
Child Dose:
Oral
Thromboembolism Prophylaxis Post-Cardiac Valve Replacement
Child: 3-6 mg/kg/day PO divided q6-8hr
Aminophylline may reverse vasodilatation effect. Useful combination with aspirin in prevention of thromboembolism. Efficacy reduced by concurrent admin of antacids. Concurrent use may increase the cardiotoxic effects of adenosine.
Potentially Fatal: Potentiates effects of oral anticoagulants and antiarrhythmic agents.
Hypersensitivity. Peptic ulcer.
Common
- Headache
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Dizziness
- Nausea
- Diarrhea
- Decreased blood pressure
>10%
Chest pain (20%),Abnormal ECG (15.9%),Dizziness (12%)
1-10%
ST-T changes (7.5%),Abdominal discomfort, oral (6.1%),Extrasystole (5%),Flushing (3.4%),Generalized pain (2.6%),Headache, oral (2.3%)
Frequency Not Defined
Myocardial infarction (rare),Ventricular arrhythmia (rare),Bronchospasm (rare),Dyspnea
Pregnancy Category B. Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
Precaution:
In patients with rapidly worsening angina, subvalvular aortic stenosis, haemodynamic instability associated with recent MI or coagulation disorders esp when given IV during myocardial imaging. Hypotension, unstable angina, aortic stenosis. Pregnancy and lactation. Safety and efficacy are not established in childn < 12 yrs.
Lactation: enters breast milk; use with caution
Symptoms: warm feeling, flushes, sweating, restlessness, weakness, dizziness, hypotension and tachycardia. Management: treatment is symptomatic. Empty stomach by gastric lavage. Haemodialysis unlikely to be useful.
Store below 25° C.
Anti-platelet drugs
Dipyridamole causes an accumulation of adenosine, adenine nucleotides and cAMP by inhibiting the activity of adenosine deaminase and phosphodiesterase thus inhibiting platelet aggregation and may cause vasodilation.
Pregnancy Category: B
Lactation: enters breast milk; use with caution
Samm Care