Uses of Rosyn: - Hypertension (high blood pressure) - Benign prostatic hyperplasia Hypertension, Benign prostatic hyperplasia Hypersensitivity to quinazoline derivatives.

How to use Terazosin: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Terazosin may be taken with or without food, but it is better to take it at a fixed time. Administration: May be taken with or without food. Give first dose and subsequent increases at bedtime to avoid syncope Adult Dose: Oral Hypertension Adult: Initially, 1 mg at bedtime, gradually increased at 7-day intervals according to response. Maintenance: 2-10 mg once daily. Max: 20 mg/day in 1 or 2 divided doses. Elderly: Initial: 0.5 mg at bed time and titrate to response Benign prostatic hyperplasia Adult: Initially, 1 mg at bedtime gradually increased at 7-day intervals according to response. Maintenance: 5-10 mg once daily. Hepatic impairment: Use with caution

Concomitant admin w/ phosphodiesterase-5 (PDE-5) inhibitors (e.g. sildenafil) can result in additive BP lowering effects and symptomatic hypotension. Possible significant hypotension when admin w/ other antihypertensive agents e.g. verapamil.

Hypersensitivity to quinazoline derivatives.

Common - Dizziness - Headache - Drowsiness - Low energy - Weakness - Palpitations - Nausea >10% Dizziness (10-20%),Asthenia (2-13%) 1-10% Hypotension (3-7%),Rhinitis/nasal congestion (2-6%),Lightheadedness (3-5%),Somnolence (3-5%),Palpitation (4%),Nausea (2-4%),Edema (3%),Sinusitis (3%),Dyspnea (2-3%),Fatigue (2.5%),Headache (2.5%),Back pain (2.4%),Flulike syndrome (2.4%),Tachycardia (2%),Amblyopia (1-2%),Blurred vision (1-2%),Impotence (1-2%),Syncope (1%)

Precaution: Prostate cancer should be ruled out before starting therapy. Patient w/ history of micturition syncope, prostate cancer, angina. Elderly. Pregnancy and lactation. Patient Counselling May impair ability to drive, operate machinery or engage in hazardous activities. Monitoring Parameters Monitor BP regularly. Lactation: Not known if excreted into breast milk; use caution

Terazosin is an alpha1-adrenoceptor antagonist which blocks peripheral postsynaptic receptors resulting to decreased arterial tone. It relaxes smooth muscle of the bladder neck causing a reduction of bladder outlet obstruction.