Uses of Revert: - Vertigo Nausea and vomiting, motion sickness, vertigo, meniere's disease, peripheral vascular diseases, cerebrovascular disorders, vestibular disorders Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.

Anti vertigo drugs

Cinnarizine provides faster relief of various symptoms of cerebral and peripheral circulation disorders and prevents attacks of vascular headache such as migraine. Cinnarizine normalizes cerebral circulation time and curves and improves cerebral irrigation in patients suffering from cerebral circulation disorders. Cinnarizine normalizes arterial pulsations in patients suffering from vasospastic disorders (Raynaud's disease). Cinnarizine significantly increases the rate of inflow of pulsations and the blood flow in the most affected limbs as well as the walking distance of patients suffering from intermittent claudication. Cinnarizine reduces the healing time of crural ulcers. Cinnarizine reduces or eliminates symptoms of vestibular disturbances like, vertigo, tinnitus and autonomic manifestations (nausea, vomiting, pallor and cold extremities) and reduces or prevents future episodes.Dimenhydrinate acts as antihistamine with anti-cholinergic properties.The substance exhibits the anti-emetic & anti vertigo effects through influencing the chemoreceptor trigger zone.

How to use Cinnarizine + Dimenhydrinate: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cinnarizine + Dimenhydrinate is to be taken with food. Administration: Should be taken with food. Adult Dose: Oral Peripheral vascular disease Adult: 75 mg bid or tid. Motion sickness Adult: 30 mg 2 hr before travel then 15 mg 8 hrly during the journey if necessary. Cerebrovascular disorders Adult: 75 mg once daily. Vertigo and vestibular disorders Adult: 30 mg tid or 75 mg 1-2 times daily. Child Dose: Oral Motion sickness Child: 5-12 yr 15 mg 2 hr before travel then 7.5 mg 8 hrly during the journey as necessary. Vertigo and vestibular disorders Child: 5-12 yr 15 mg tid.

Cinnarizine: CNS depressant effect enhanced with alcohol. Action potentiated by domperidone. Dimenhydrinate: Physically incompatible with aminophylline, hydrocortisone, phenothiazines and some barbiturates in solution. Potentially Fatal: Potentiates the sedative effects of CNS depressants including alcohol, barbiturates, opioid analgesics, sedatives and neuroleptics. MAOIs, atropine, TCAs enhance antimuscarinic effect. Masks ototoxicity produced by aminoglycoside antibiotics.

Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.

Common - Drowsiness - Headache - Stomach pain - Dryness in mouth Extrapyramidal symptoms sometimes associated with severe depression. Drowsiness, headache, GI upsets, unsteadiness, headache; rarely skin and hypersensitivity reactions, dry mouth, blurred vision, urinary difficulty or retention, constipation and increased gastric reflux, fatigue. Hypolipidaemic effect.

The safety of the combination of Cinnarizine & Dimenhydrinate in human pregnancy has not been established. The combination of Cinnarizine & Dimenhydrinate is excreted in human breast milk and should not be taken by women who are breast feeding.

Precaution: Hypotension; pregnancy; lactation; elderly. May impair ability to drive or operate machineries.

Drowsiness, dizziness and ataxia with anticholinergic effects such as dry mouth, flushing of the face, dilated pupils, tachycardia, pyrexia, headache and urinary retention. General supportive measures should be used to treat respiratory insufficiency or circulatory failure. Gastric lavage with isotonic sodium chloride solution is recommended.

Store in a cool (below 30°C) and dry place. Keep away from light and out of reach of children.

Anti vertigo drugs

Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity. Dimenhydrinate is an antihistamine which also has antimuscarinic and central sedative action. It also exerts a depressant action on hyperstimulated labyrinthine function.

Dimenhydrinate and cinnarizine should not be used during pregnancy and lactation.