Prostalex 250 mg
Flutamide
Category: Tablet
Manufacturer: Beacon Pharmaceuticals Ltd.
Medicine Selling service is not available yet.
Related Medicines
Uses of Prostalex:
- Prostate cancer
Prostate cancer
Hypersensitivity, severe hepatic impairment, pregnancy and lactation.
Hormonal Chemotherapy
Flutamide is a nonsteroidal 'pure' antiandrogen which acts directly on the target tissues either by blocking androgen uptake or by inhibiting cytoplasmic and nuclear binding of androgen.
How to use
Flutamide:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
Flutamide may be taken with or without food, but it is better to take it at a fixed time.
Administration:
May be taken with or without food.
Adult Dose:
Oral
Palliative treatment of prostatic carcinoma
Adult: 250 mg tid preferably at least 3 days before gonadorelin analogue treatment.
Increased prothrombin time in patients on long-term warfarin treatment.
Hypersensitivity, severe hepatic impairment, pregnancy and lactation.
Common
- Breast enlargement in male
- Sleepiness
- Nausea
- Abdominal pain
- Anemia (low number of red blood cells)
- Breast tenderness
- Constipation
- Decreased appetite
- Decreased libido
- Depression
- Dizziness
- Indigestion
- Flatulence
- Hot flashes
- Increased liver enzymes
- Rash
- Weakness
- Weight gain
>10%
Hot flashes (61%),Decreased libido (36%),Impotence (31%),Diarrhea (12%),Nausea/vomiting (11%)
1-10%
Gynecomastia (9%),Anorexia (4%),Edema (4%),Leukopenia (3%),Rash (3%)
Frequency Not Defined
Hemolytic anemia, methemoglobinemia
Increased AST, ALT, bilirubin, BUN
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Precaution:
Perform liver function tests before starting treatment and at regular intervals. Treatment is not recommended in patients whose ALT values exceed twice the upper limit of normal. Regular assessment of prostate specific antigen level may help to monitor disease progression. Advise patient against discontinuing drug on their own. Exercise caution in patients with cardiac disease.
Lactation: Excretion in milk unknown; not recommended
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Hormonal Chemotherapy
Flutamide is a nonsteroidal 'pure' antiandrogen which acts directly on the target tissues either by blocking androgen uptake or by inhibiting cytoplasmic and nuclear binding of androgen.
Pregnancy Category: D
Lactation: Excretion in milk unknown; not recommended
Samm Care