Emotional disturbance, anxiety, tension, fatigue, depression, headache, sleep disorder, body ache, gastric problems etc.
Combined anxiolytics & anti-depressant drugs.
Tricyclic antidepressants, such as nortriptyline hydrochloride, are used to treat depression. Nortriptyline reduces norepinephrine and serotonin absorption at nerve terminals. Nortriptyline has a higher effect on norepinephrine reuptake than on serotonin reuptake than its parent chemical amitriptyline, which is equally effective in blocking norepinephrine and serotonin absorption.
Fluphenazine is a phenothiazine tranquilizer with a piperazine side chain. Fluphenazine is predominantly a neuroleptic medication, with the main therapeutic action thought to be strong dopamine (especially D2 ) receptor antagonism.
Adult: One tablet three times daily. The course of the treatment should be limited to three months. If the patient does not respond after 4 weeks, an alternative treatment should be given.
Children: Not indicated for the treatment of children.
Elderly: Elderly patients should be started on one tablet twice daily. If one tablet three times a day required subsequently three tablets may be given.
Dry mouth, sleepiness, constipation, tachycardia, nasal congestion, impaired vision, and excitation are all symptoms.
Unless there are compelling reasons, do not use during pregnancy, especially in the early and final trimesters. There is no proof of medication safety in human pregnancy, and animal trials have had inconclusive outcomes. Breastfeeding is not advised for women who are receiving this combo.
Patients suffering from glaucoma, prostate enlargement, heart failure, and myocardial infarction. The medication may affect awareness and ability to operate machines or drive a car.
Store at temperatures below 25 degrees Celsius. Keep out of direct sunlight and dampness.
Fluphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain & Nortriptyline either inhibits the reuptake of the neurotransmitter serotonin at the neuronal membrane or acts at beta-adrenergic receptors.
