Oxifun 1% Cream

    Oxifun 1%

    Generic: Oxiconazole Nitrate

    Category: Cream

    Manufacturer: Square Pharmaceuticals Ltd.

    Price: 50.33

    10 gm tube

    Indications

    Oxiconazole topical preparation is indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum. Oxiconazole Cream is indicated for the topical treatment of tinea (pityriasis) versicolor due to Malassezia furfur.

    Interaction

    Potential drug interactions between Oxiconazole and other drugs have not been systematically evaluated.

    Contraindications

    Oxiconazole topical preparation is contraindicated in individuals who have shown previous hypersensitivity to Oxiconazole

    Side Effects

    Pruritus, burning, irritation and allergic contact dermatitis, folliculitis, erythema, and papules, fissure, maceration, rash, stinging and nodules.

    Precautions And Warnings

    Oxiconazole topical preparation is not for ophthalmic or intravaginal use.

    Storage Conditions

    Store in a cool and dry place,protected from light. Do not freeze.

    Drug Classes

    Topical Antifungal preparations

    Mode of Action

    This topical preparation contains the antifungal active compound Oxiconazole Nitrate. For topical dermatological use only. Oxiconazole Nitrate is an imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has in vitro activity against a wide range of pathogenic fungi. Oxiconazole has been shown to be active against most strains of the following organisms both in vitro and in clinical infections at indicated body sites: Epidermophyton floccosum, Trichophyton mentagrophytes, Trichophyton rubrum, Malassezia furfur. Oxiconazole exhibits satisfactory in vitro minimum inhibitory concentrations (MICs) against most strains of the following organisms: Microsporum audouini, Microsporum canis, Microsporum gypseum, Trichophyton tonsurans,Trichophyton violaceum.

    Pregnancy Category

    Pregnancy category B. Because Oxiconazole Nitrate is excreted in human milk, caution should be exercised when the drug is administered to a nursing woman.
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