Orobac 200 200 mg
Cefditoren
Category: Tablet
Manufacturer: Incepta Pharmaceuticals Ltd.
Allopathic
MFG. Licence No. Biological
193
MFG. Licence No. Non-Biological
108
Address
Zirabo, Savar, Dhaka Dewan Idris Road, Bara Rangamatia
Price: 1080.0 ৳
Box
Medicine Selling service is not available yet.
Related Medicines
Uses of Zostum-O Tablet:
- Bacterial infections
Pharyngitis, Community-acquired pneumonia, Susceptible infections, Tonsillitis, Soft tissue infections, Respiratory tract infections, Acute Exacerbations of Chronic bronchitis
Hypersensitivity to Cefditoren, other cephalosporins; or milk proteins. Carnitine deficiency.
Third generation Cephalosporins
Cefditoren inhibits the synthesis of bacterial cell wall. It has high affinity to penicillin-binding proteins (PBPs) in various bacteria, showing a bactericidal effect.
How to use Zostum-O Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
Cefditoren is to be taken with food.
Administration:
Should be taken with food.
Adult Dose:
Oral
Community-acquired pneumonia
Adult: 400 mg bid for 14 days.
Acute bacterial exacerbation of chronic bronchitis
Adult: 400 mg bid for 10 days.
Pharyngitis ; Tonsillitis; Uncomplicated skin and skin structure infections
Adult: 200 mg bid for 10 days.
Child Dose:
<12 years old: Safety & efficacy not established
>12 years old: As in adults
Renal Dose:
Renal impairment:
CrCl (ml/min)
30-49 Maximum: 200 mg bid
<30 Maximum: 200 mg once daily
Reduced oral bioavailability when coadministered with antacids or H2-receptor antagonists. Probenecid may increase plasma concentration and prolong half-life of Cefditoren. May enhance anticoagulant effect of vitamin K antagonists (e.g. warfarin).
Hypersensitivity to Cefditoren, other cephalosporins; or milk proteins. Carnitine deficiency.
Common
- Nausea
- Indigestion
- Stomach pain
- Diarrhea
>10%
Diarrhea (11-15%)
1-10%
Nausea (4-6%),Headache (2-3%),Abdominal pain (2%),Dyspepsia (1-2%),Vomiting (1%)
<1%
Bacterial/fungal superinfection,C. difficile colitis,Hypersensitivity,Increased bleeding time,Stevens-Johnson syndrome,Vaginal moniliasis
Potentially Fatal: Hypersensitivity, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis.
Pregnancy category B. There are no adequate and well-controlled studies in pregnant women. Cefditoren should be used during pregnancy only if clearly needed.Lactation: Animal studies show that Cefditoren excreted in breast milk. Caution should be exercised when Cefditoren is administered to nursing women.
Precaution:
Pregnancy and lactation. Patients with penicillin allergy. Avoid prolonged use as pivalate-containing compounds may cause carnitine deficiency over time; greater risk of carnitine deficiency in patients with renal impairment or decreased muscle mass. May decrease prothrombin activity especially in patients with renal or hepatic impairment, poor nutritional status, prolonged antibiotic treatment or patients previously stabilised on anticoagulant therapy. Long term use may result in development of drug-resistant bacteria, or superinfection including Clostridium difficile-associated diarrhoea and pseudomembranous colitis.
Lactation: excretion in milk unknown; use with caution
Information on Cefditoren overdosage in humans is not available. However, with other ß-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions. Hemodialysis may aid in the removal of Cefditoren from the body, particularly if renal function is compromised.
Store in a cool (below 25°C) and dry place protected from light.
Third generation Cephalosporins
Cefditoren is a third generation cephalosporin used for treatment of susceptible infections caused by gram-positive and gram-negative bacteria. It inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs).
Pregnancy Category: B
Lactation: excretion in milk unknown; use with caution
Samm Care