Orlo 5 mg/5 ml Suspension

    Orlo 5 mg/5 ml

    Loratadine

    Category: Suspension

    Manufacturer: Avarox Pharmaceuticals Ltd.

    Price: 25.0

    60 ml in Bottle

    Uses of Orlo: - Allergic conditions
    Non-sedating antihistamines
    Loratadine is a tricyclic antihistamine with selective peripheral histamine H1-receptor antagonistic activity. It is devoid of anticholinergic activity. It is rapidly effective and long-lasting, allowing once-a-day administration.
    How to use Loratadine: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Loratadine is to be taken empty stomach.
    There are no reports of potentially hazardous interactions with other drugs. In contrast to many other histamine H1 receptor antagonists, Loratadine has no potentiating effects when administered concurrently with alcohol, as measured by psychomotor performance studies. Concomitant therapy with drugs that inhibit or are metabolized by hepatic cytochromes P450 3A4 and 2D6 may elevate plasma concentrations of either drug and this mayifesult in adverse effects. Cimetidine inhibits both enzymes while erythromycin or ketoconazole inhibits P450 3A4. These drugs increase loratadine serum concentrations but no adverse effects are reported.
    Loratadine is contraindicated in patients who have shown hypersensitivity or idiosyncrasy to their components.
    Common - Sleepiness - Increased appetite
    US FDA Pregnancy Category of Loratadine is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Loratadine have been shown to be excreted in human milk. So, caution should be exercised when Loratadine is administered to a nursing woman.
    Caution should be taken in patients with liver impairment or renal insufficiency (eGFR <30 ml/min).
    In adults somnolence, tachycardia and headache have been reported with overdose greater than 10 mg. Extrapyramidal signs and palpitations have been reported in children with overdoses of greater than 10 mg. In the event of overdosage, general symptomatic and supportive measures should be instituted promptly and maintained for as long as necessary. It would seem reasonable to treat patients presenting early after large overdoses with oral activated charcoal. The conscious patients may be induced to vomit or gastric lavage may be performed.
    Keep in a dry place away from light and heat. Keep out of the reach of children.
    Non-sedating antihistamines
    This tablet is a preparation of Loratadine. Loratadine is a non-sedative histamine Hr receptor antagonist with antiallergic properties. Loratadine is a long-acting tricyclic antihistamine with selective peripheral Hi-receptor antagonistic activity and no central sedative or anticholinergic effect. It is rapidly effective and long-lasting, allowing once-a-day administration.
    There is no experience of the use of Loratadine in human pregnancy. Therefore its use during pregnancy is not advisable. Loratadine is excreted in breast milk in a very small amount. So nursing mothers are advised not to take the drug.
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