Mucurel 300 mg
Erdosteine
Category: Capsule
Manufacturer: Aristopharma Ltd.
Medicine Selling service is not available yet.
Related Medicines
Uses of Mucurel:
- respiratory tract disorders associated with viscid mucus
Symptomatic treatment of acute exacerbations of, chronic bronchitis, in adults as an expectorant.
Hypersensitivity to the active substance or to any of the other excipients. Active peptic ulcer.
Cough expectorants & mucolytics
Erdosteine is a prodrug that is metabolised into N-thiodiglycolyl-homocysteine whereby free thiol groups are formed leading to the opening of the disulphide bonds of the bronchial mucoproteins, thus reducing the viscosity of mucus and purulent sputum. It also antagonises the local formation of free radicals and inhibits elastase enzyme activity and bacterial adhesion to epithelial cells.
How to use
Erdosteine:
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it.
Erdosteine may be taken with or without food, but it is better to take it at a fixed time.
Administration:
The capsules must be swallowed whole with a glass of water.
Adult Dose:
Oral
As a mucolytic
Adult: 300 mg bid. Max duration: 10 days.
Hepatic Failure
Since there are no data in patients with severe liver failure, the use of erdosteine is not recommended in these patients.
Mild to Moderate Hepatic Failure
Dose should be reduced
Renal Dose:
Since there are no data in patients with creatinine clearance <25ml/min, the use of erdosteine is not recommended in these patients.
Hypersensitivity to the active substance or to any of the other excipients. Active peptic ulcer.
Common
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Increased sweating
- Nausea
- Vertigo
- Vomiting
Epigastralgia, nausea, vomiting, loose stools, spasmodic colitis, headache.
The use of Erdosteine in pregnant or breast-feeding women is not recommended.
Precaution:
Pregnancy, lactation.
Keep in a dry place away from light and heat. Keep out of reach of children
Cough expectorants & mucolytics
Erdosteine contains two sulfhydryl groups, which are freed after metabolic transformation in the liver. The liberated sulfhydryl groups break the disulphide bonds, which hold the glycoprotein fibres of mucus together. This makes the bronchial secretions more fluid and enhances elimination.
The use of Erdosteine in pregnant or breast-feeding women is not recommended.
Samm Care