Moxodin 0.4 4 mg Tablet

    Moxodin 0.4 4 mg

    Moxonidine

    Category: Tablet

    Manufacturer: Square Pharmaceuticals PLC, Pabna

    Uses of Moxodin 0.4: - Hypertension (high blood pressure) Hypertension Conduction disorders; bradycardia; severe arrhythmias; severe heart failure; severe ischaemic heart disease; history of angioedema; severe liver or renal impairment; Raynaud's syndrome; intermittent claudication; epilepsy; depression; Parkinson's disease; glaucoma. Pregnancy and lactation.
    How to use Moxonidine: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Moxonidine may be taken with or without food, but it is better to take it at a fixed time. Administration: May be taken with or without food. Adult Dose: Oral Hypertension Adult: 200 mcg once daily, increase if necessary after 3 wk to 400 mcg daily as single or in 2 divided doses. If necessary, after a further 3 wk, increase to 600 mcg daily in 2 divided doses. Max: 600 mcg daily. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation 30-60 Single dose should not exceed 200 mcg. Max daily dose 400 mcg. <30 Avoid
    Additive effects with other antihypertensives; may increase sedative effects of benzodiazepines. Effects may be antagonised by TCAs.
    Conduction disorders; bradycardia; severe arrhythmias; severe heart failure; severe ischaemic heart disease; history of angioedema; severe liver or renal impairment; Raynaud's syndrome; intermittent claudication; epilepsy; depression; Parkinson's disease; glaucoma. Pregnancy and lactation.
    Common - Dryness in mouth - Headache - Rash - Dizziness - Back pain - Insomnia (difficulty in sleeping) - Sleepiness - Vomiting - Weakness - Nausea - Diarrhea - Vertigo Dry mouth; headache; fatigue; dizziness; nausea; sleep disturbances; asthenia; vasodilatation; skin reactions; constipation; depression; anxiety; anorexia; parotid pain; vivid dreams; impotence and loss of libido; urinary retention or incontinence; slight orthostastic hypotension; fluid retention.
    Precaution: Renal impairment; avoid abrupt withdrawal (if concomitant treatment with ?-blocker has to be stopped, discontinue ?-blocker first, then moxonidine after few days).
    If you (or someone else) swallow a lot of the tablets all together, or if you think a child has swallowed any of the tablets, contact your nearest hospital casualty department or your doctor immediately. An overdose is likely to cause headache, sleepiness, dry mouth, loss of balance, dizziness, low blood pressure, slowing of the pulse, vomiting, feeling tired, weakness and pain in your stomach. Please take this leaflet, any remaining tablets and the container with you to the hospital or doctor so that they know which tablets were consumed.
    Do not store above 30° C. Keep blister in the outer carton in order to protect from light
    Anti-hypertensive
    Moxonidine is a centrally-acting antihypertensive. It acts in the brainstem through stimulation of central imidazoline receptors to reduce sympathetic tone. Moxonidine also has a low affinity for alpha2-adrenoceptors.
    Moxonidine is not recommended if you are pregnant, planning on becoming pregnant or are breastfeeding. Ask your doctor or pharmacist for advice before taking any medicine if you are pregnant or breastfeeding.
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