Peptic ulcer, Infantile colic, Upper GI bloating, Functional dyspepsia, Spastic or irritable colon There is no information about the contraindication of Simethicone.

Anti-dyspeptic/Carminatives

Simethicone is used as an antiflatulent to relieve symptoms commonly referred to gas including upper GI bloating, pressure, fullness or stuffed feeling. The clinical use of Simeticone is based on its antifoaming properties. Its antifoaming action relieves flatulence by dispersing and preventing the formation of mucous surrounded gas pockets in the GI tract. Simeticone acts in the stomach and intestines to change the surface tension of gas bubbles, enabling them to coalesce; thus gas is freed and eliminated more easily by belching or passing flatus. Simeticone aids in the elimination of gas from the GI tract and can be used to reduce postoperative gas pains. Simeticone can also be used prior to gastroscopy to enhance visualization and prior to radiography of the intestine to reduce gas shadows.

Administration: Should be taken after meals and at bedtime Adult Dose: Adults: 40 to 125 mg (0.6 to 1.9 ml drops) 4 times daily up to 500 mg/day (7.5 ml drops). OR 1-3 chewable tablets; 4 times daily, up to 500 mg/day (12 chewable tablets). Child Dose: Children older than 12 years of age: 40 to 80 mg (0.6 to 1.2 ml drops) 4 times daily up to 500 mg/day (7.5 ml drops). Children 2 to12 years of age: 40 mg (0.6 ml drops) 4 times daily. Children younger than 2 years of age: 20 mg (0.3 ml drops) 4 times daily up to 240 mg/day (3.6 ml drops).

There is no evidence that Simethicone modifies the effect of other drugs. The defoaming effect of Simethicone is reduced by antacids such as Aluminium Hydroxide and Magnesium Carbonate, which absorb the Silicone.

There is no information about the contraindication of Simethicone.

Simethicone is physiologically inert and no adverse effect has been reported after oral ingestion. Loose stools.

Pregnant women: No data are available to suggest any harmful effects.Lactating mother: Excretion of simethicone in breast milk has not been established, and would be most unlikely.

Precaution: More than 12 doses per day should not be used, except under the advice and supervision of a physician. Keep the medicine out of the reach of children.

Should be stored in cool and dry place, protected from light. Keep the medicine out of the reach of children.

Anti-dyspeptic/Carminatives

Changes surface tension of gas bubbles and causes collapse of foam bubbles, thus allowing easier passage of gas and preventing gas pockets in gastrointestinal tract.

Pregnant women: No data are available to suggest any harmful effects.Lactating mother: Excretion of simethicone in breast milk has not been established, and would be most unlikely.