Cleansing of the colon Sodium Phosphates is contraindicated in diseases where high sodium, high phosphorus or low calcium levels may be encountered. Known allergy or hypersensitivity to sodium phosphate salts or any component Biopsy-proven acute phosphate nephropathy, Gastrointestinal (GI) obstruction, Gastric bypass or stapling surgery, Bowel perforation, Toxic colitis, Toxic megacolon.

Enema & bowel cleansing solution

It acts as a saline laxative when administered by the rectal route. Fluid accumulation in the lower bowel produces distension and promotes peristalsis and bowel movement on the rectum, sigmoid and descending colon. These phenomena results in rapid evacuation.

Administration: Remove orange protective shield from enema tip before inserting; with steady pressure, gently insert enema tip into rectum with a slight side-to-side movement, with tip pointing toward navel Insertion may be easier if person receiving enema bears down, as if having a bowel movement; this helps relax the muscles around the anus Do not force enema tip into rectum as this can cause injury Squeeze bottle until nearly all liquid is gone; it is not necessary to empty the bottle completely, as it contains more liquid than needed Remove enema tip from rectum and maintain position until urge to evacuate is strong (usually 1-5 minutes) Do not retain enema solution for more than 10 minutes Positions for using this enema Left-side position: Lie on left side with knee bent, and arms resting comfortably Knee-chest position: Kneel, and then lower head and chest forward until left side of face is resting on surface with left arm folded comfortably Adult Dose: Oral Tablets are indicated for cleansing of the colon as a preparation for colonoscopy in adults 18 years of age or older. Evening before the colonoscopy: Four tablets with 8 ounces (oz.) of clear liquids every 15 minutes (for a total of 20 tablets). Day of colonoscopy (starting 3 to 5 hours before the procedure): Four tablets with 8 oz. of clear liquids every 15 minutes (for a total of 12 tablets). As Rectal Enema Constipation & Bowel Cleansing 1 bottle PR; not to exceed 1 administration/24 hr Child Dose: As Rectal Enema Constipation & Bowel Cleansing Indicated as laxative in the relief of occasional constipation and as part of a bowel cleansing regimen in preparing the colon for surgery, x-ray or endoscopic examination <2 years: Do not use 2-4 years: Administer one-half bottle PR of pediatric enema (ie, ~30 mL); prepare dose by unscrewing cap from bottle and removing 2 tablespoons of liquid (30 mL) with a measuring spoon, replace cap and administer remaining liquid 5-11 years: Administer 1 bottle PR of pediatric enema (ie, 59 mL) 12 years or older: Administer as in adults (adult enema) Renal Dose: Use with caution

Use with caution in patients taking calcium channel blockers, diuretics, lithium treatment or other medications that might affect electrolyte levels as hyperphosphataemia, hypocalcaemia, hypokalae- mia, hypernatraemic dehydration and acidosis may occur. No other sodium phosphate preparations including sodium phosphate oral solution or tablets should be given concomitantly. As hypernatraemia is associated with lower lithium levels, concomitant use of this medicine and lithium therapy could lead to a fall in serum lithium levels with a lessening of effectiveness.

Sodium Phosphates is contraindicated in diseases where high sodium, high phosphorus or low calcium levels may be encountered. Known allergy or hypersensitivity to sodium phosphate salts or any component Biopsy-proven acute phosphate nephropathy, Gastrointestinal (GI) obstruction, Gastric bypass or stapling surgery, Bowel perforation, Toxic colitis, Toxic megacolon.

Hypersensitivity,Pruritus,Dehydration,Hyperphosphatemia,Hypocalcemia,Hypokalemia,Hypernatremia,Metabolic acidosis,Nausea,Vomiting,Abdominal pain,Abdominal distension,Diarrhea,Gastrointestinal pain,Chills,Blistering,Stinging,Anal discomfort,Proctalgia

As there is no relevant data available to evaluate the potential for fetal malformation or other feto-toxic effects when administered during pregnancy it should only be used as directed by a physician at the time of delivery or postpartum. As sodium phosphate may pass into the breast milk, it is advised that breast milk is expressed and discarded for at least 24 hours after receiving this medicine.

Precaution: Phosphorus replacement therapy with sodium phosphates should be guided primarily by the serum inorganic phosphorus levels and the limits imposed by the accompanying sodium (Na+) ion. Frequent monitoring of serum calcium and sodium as well as renal function is recommended. Use with caution in patients with renal impairment, cirrhosis, cardiac failure or in conjunction with other edema causing medications. It should not be used with sodium retaining medications. Caution must be exercised in the administration of parenteral fluids especially those containing sodium ion, to patients receiving corticosteroids or corticotropin. Lactation: Unknown whether distributed in breast milk; caution because of risk for electrolyte disturbances or dehydration

Using more than 133 ml in 24 hours can be harmful. In case of excessive dose, recovery from the toxic effects can normally be achieved by rehydration. Treatment of electrolyte imbalance may require immediate medical intervention with appropriate electrolyte and fluid replacement therapy.

Store below 25° C. Protect from light. Do not refrigerate. Keep out of the reach of children.

Enema & bowel cleansing solution

Saline cathartic effect. Draws water into the lumen of the gut where it causes osmotic effect; causes abdominal distention and promotes peristalsis and evacuation of the bowel.

Pregnancy Category: C Lactation: Unknown whether distributed in breast milk; caution because of risk for electrolyte disturbances or dehydration