Flurbi 50 mg
Flurbiprofen
Category: Tablet
Manufacturer: Sharif Pharmaceuticals Ltd.
Allopathic
MFG. Licence No. Biological
281
MFG. Licence No. Non-Biological
487
Address
Barabo, Tarabo, Rupganj, Narayanganj
Medicine Selling service is not available yet.
Related Medicines
Uses of Flurbi Gel:
- Pain relief
Dysmenorrhoea, Sore throat, Ocular inflammation, Pain and inflammation associated w/ musculoskeletal and joint disorders, Prophylaxis of miosis during ocular surgery
Peptic ulcer, GI haemorrhage, asthma, bronchospasm, rhinitis, angioedema, hypersensitivity; aspirin intolerance; pregnancy (3rd trimester); lactation.
Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Flurbiprofen inhibits prostaglandin synthesis by decreasing the activity of cyclooxygenase resulting in reduced prostaglandin levels. It is also a potent inhibitor of platelet aggregation.
How to use
Flurbiprofen Gel:
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
Administration:
Should be taken with food.
Adult Dose:
Oral
Pain and inflammation
Adult: 150-200 mg daily in divided doses, increased to 300 mg daily in acute or severe conditions if necessary.
Dysmenorrhoea
Adult: Initially, 100 mg followed by 50-100 mg 4-6 hrly. Max: 300 mg daily.
Rheumatoid Arthritis, Osteoarthritis
200-300 mg/day divided q6-12hr PO, not to exceed 100 mg/dose or 300 mg/day
Child Dose:
<12 years: Not recommended
Renal Dose:
Renal Impairment
Severe Impairment: Not recommended
Reduced antihypertensive effect of ACE inhibitors, angiotensin II receptor antagonists and ?-blockers. Slight reduction in blood glucose concentration in patients w/ DM receiving certain antidiabetic agents (e.g. glyburide, metformin). Reduced diuretic effect of furosemide and thiazides. May increase toxicity of lithium and methotrexate. May increase risk of bleeding w/ antiplatelets, anticoagulants, SSRIs, corticosteroids.
Peptic ulcer, GI haemorrhage, asthma, bronchospasm, rhinitis, angioedema, hypersensitivity; aspirin intolerance; pregnancy (3rd trimester); lactation.
Common
- No common side effects seen
Oedema, abdominal pain, constipation, diarrhoea, dyspepsia/heartburn, liver enzyme elevations, flatulence, nausea, vomiting, wt change, headache, nervousness, CNS stimulation (e.g. anxiety), CNS inhibition (e.g. somnolence), rhinitis, vision changes, dizziness/vertigo, tinnitus, signs and symptoms of UTI, rash. Ocular hyperaemia, eye irritation, fibrosis, miosis, mydriasis.
Potentially Fatal: GI bleeding, ulceration and perforation, jaundice, fulminant hepatitis, liver necrosis, hepatic failure.
Pregnancy Category C. Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Precaution:
Patients w/ known CV disease or risk factors for CV disease, fluid retention. Hepatic and renal impairment. Lactation.
Lactation: excreted in breast milk; not recommended
Symptoms: Headache, nausea, vomiting, epigastric pain, GI bleeding, diarrhoea, disorientation, excitation, coma, drowsiness, dizziness, tinnitus, fainting and occasionally convulsions, acute renal failure and liver damage. Management: Supportive and symptomatic treatment. Admin activated charcoal w/in 1 hr after ingestion. In adults, gastric lavage should be considered.
Store between 15-25° C.
Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Flurbiprofen inhibits prostaglandin synthesis by decreasing the activity of cyclooxygenase resulting in reduced prostaglandin levels. It is also a potent inhibitor of platelet aggregation.
Pregnancy Category: C; avoid in late pregnancy
Lactation: excreted in breast milk; not recommended
Samm Care