Epastat 50 50 mg
Epalrestat
Category: Tablet
Manufacturer: Opsonin Pharma Limited
Allopathic
MFG. Licence No. Biological
012
MFG. Licence No. Non-Biological
080
Address
Rupatali,
Price: 100.8 ৳
Strip
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Related Medicines
Uses of Epastat 50:
- Diabetic nerve pain
Diabetic neuropathy
Hypersensitivity. Pregnant or breastfeeding.
Aldose reductase inhibitor
Epalrestat is aldose reductase inhibitor. The aldose reductase inhibitors have a distinct mechanism of action, affecting the underlying disease process in diabetic neuropathy, although the extent of the polyol pathway involvement is yet to be determined. This medicine suppresses accumulation of sorbitol in cells by inhibiting action of aldose reductase which converts glucose of sugar to sorbitol. Epalrestat may improve motor and sensory nerve conduction velocity and subjective neuropathy symptoms.
How to use
Epalrestat:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
Epalrestat may be taken with or without food, but it is better to take it at a fixed time.
Adult Dose:
Oral
Diabetic neuropathy
Adult: 50 mg tid.
There are no known drug interactions and none well documented.
Hypersensitivity. Pregnant or breastfeeding.
Common
- Nausea
- Vomiting
- Abnormal liver function
The most commonly reported adverse reactions include abdominal pain, nausea, rash, itch, erythema and blister.
Pregnancy category is not classified. FDA has not yet classified the drug into a specified pregnancy category
Precaution:
Urine may turn yellowish brown or reddish after taking the medicine, because the yellowish brown or reddish color is attributed to components of this medicine.
Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
Aldose reductase inhibitor
Epalrestat is aldose reductase inhibitor. The aldose reductase inhibitors have a distinct mechanism of action, affecting the underlying disease process in diabetic neuropathy, although the extent of the polyol pathway involvement is yet to be determined. Epalrestat reduces sorbitol accumulation in the sciatic nerve, erythrocytes. Epalrestat may improve motor and sensory nerve conduction velocity and subjective neuropathy symptoms.
Pregnancy category is not classified. FDA has not yet classified the drug into a specified pregnancy category
Samm Care