Uses of Dinaran: - Motion sickness - Vertigo - Meniere's disease Nausea and vomiting, motion sickness, vertigo, meniere's disease, peripheral vascular diseases, cerebrovascular disorders, vestibular disorders Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.

Anti vertigo drugs

Cinnarizine acts as an antihistamine, labyrinthine sedative and a peripheral antivasoconstrictor. Cinnarizine is a selective calcium antagonist, inhibiting the influx of Ca2+ intracellularly. It prevents the Ca2+ dependent contraction of arterial smooth muscle by inhibiting Ca2+ influx through smooth muscle calcium channels and thereby, improves vestibular symptoms and prevents peripheral arterial disease

How to use Cinnarizine: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cinnarizine is to be taken with food. Administration: Should be taken with food. Adult Dose: Oral Peripheral vascular disease Adult: 75 mg bid or tid. Motion sickness Adult: 30 mg 2 hr before travel then 15 mg 8 hrly during the journey if necessary. Cerebrovascular disorders Adult: 75 mg once daily. Vertigo and vestibular disorders Adult: 30 mg tid or 75 mg 1-2 times daily. Child Dose: Oral Motion sickness Child: 5-12 yr 15 mg 2 hr before travel then 7.5 mg 8 hrly during the journey as necessary. Vertigo and vestibular disorders Child: 5-12 yr 15 mg tid.

CNS depressant effect enhanced with alcohol. Action potentiated by domperidone. Increased sedative effect w/ CNS depressants or TCAs.

Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.

Common - Sleepiness - Nausea - Weight gain - Indigestion Extrapyramidal symptoms sometimes associated with severe depression. Drowsiness, headache, GI upsets, unsteadiness, headache; rarely skin and hypersensitivity reactions, dry mouth, blurred vision, urinary difficulty or retention, constipation and increased gastric reflux, fatigue. Hypolipidaemic effect.

The safety of Cinnarizine in human pregnancy has not been established although studies in animals have not demonstrated teratogenic effects. Therefore, it is not advisable to administer Cinnarizine in pregnancy

Precaution: Hypotension; pregnancy; lactation; elderly. May impair ability to drive or operate machineries.

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity.