Dilatrol 5 mg/5 ml Syrup

    Dilatrol 5 mg/5 ml

    Bambuterol Hydrochloride

    Category: Syrup

    Manufacturer: Eskayef Pharmaceuticals Ltd. Mirpur.

    Uses of Dilatrol: - Asthma - Chronic obstructive pulmonary disease (COPD) Chronic obstructive pulmonary disease (COPD), Asthma. Severe hepatic impairment; cirrhosis.
    Short-acting selective & β2-adrenoceptor stimulants
    Bambuterol is an adrenergic β2 receptor agonist which predominantly stimulates β2 receptor, thus producing relaxation of bronchial smooth muscle, inhibition of release of endogenous spasmogens, inhibition of edema caused by endogenous mediators & increased mucocilliary clearance.
    How to use Bambuterol Hydrochloride: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bambuterol Hydrochloride may be taken with or without food, but it is better to take it at a fixed time. Adult Dose: Adult: PO 10-20 mg/day at bedtime. Hepatic impairment: Severe: Not recommended. Renal Dose: Renal impairment: CrCl (ml/min) <50 Initial dose should be halved.
    Risk of hypokalaemia increased by co-admin of corticosteroids, diuretics or xanthines. Prolong the action of drugs e.g. suxamethonium.
    Severe hepatic impairment; cirrhosis.
    Common - Insomnia (difficulty in sleeping) - Headache - Palpitations - Restlessness - Muscle cramp - Trembling Fine tremor of skeletal muscle (e.g. hands), palpitations and muscle cramps; tachycardia, tenseness and peripheral vasodilation.
    Pregnant women: There is no definite evidence of ill consequence during pregnancy. Nevertheless, the drug should not be used during the first trimester of pregnancy, unless the expected benefit is thought to outweigh any possible risk to the fetus.Lactating mother: It is excreted in breast milk. So, patients taking this drug should not breast-feed.
    Precaution: DM, hyperthyroidism, myocardial insufficiency, arrhythmias, susceptibility to QT-interval prolongation. Pregnancy.
    Keep away from light, store in a cool and dry place. Keep out of reach of children.
    Short-acting selective & β2-adrenoceptor stimulants
    Bambuterol HCl is a prodrug of terbutaline. It relaxes bronchial smooth muscle by selectively acting on ?2-receptors.
    Pregnant women: There is no definite evidence of ill consequence during pregnancy. Nevertheless, the drug should not be used during the first trimester of pregnancy, unless the expected benefit is thought to outweigh any possible risk to the fetus.Lactating mother: It is excreted in breast milk. So, patients taking this drug should not breast-feed.
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