Carbate 100 mcg/ml
Carbetocin
Category: IV Injection
Manufacturer: Incepta Pharmaceuticals Ltd.
Allopathic
MFG. Licence No. Biological
193
MFG. Licence No. Non-Biological
108
Address
Zirabo, Savar, Dhaka Dewan Idris Road, Bara Rangamatia
Price: 135.0 ৳
1ml amps
1 ml ampoule
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Related Medicines
Prophylaxis of uterine atony and excessive bleeding after caesarean section
Do not administer before delivery. Vascular disease esp coronary artery disease; hepatic or renal disease.
Drugs acting on the Uterus
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin; it causes contraction of the uterus. Carbetocin binds to oxytocin receptors present on the smooth musculature of the uterus, resulting in rhythmic contractions of the uterus, increased frequency of existing contractions, and increased uterine tone. The oxytocin receptor content of the uterus is very low in the non-pregnant state, and increases during pregnancy, reaching a peak at the time of delivery.
Adult Dose:
Intravenous
Prophylaxis of uterine atony and excessive bleeding after caesarean section
Adult: Single dose of 100 mcg given over 1 min after delivery.
Vasoconstrictors in conjunction with caudal block anaesthesia; cyclopropane anaesthesia.
Do not administer before delivery. Vascular disease esp coronary artery disease; hepatic or renal disease.
Nausea; vomiting; abdominal pain; pruritus; flushing; feeling of warmth; hypotension; headache; tremor; back pain; dizziness; metallic taste; anaemia; sweating; chest pain; dyspnoea; chills; tachycardia; anxiety.
Use of carbetocin injection is contraindicated during pregnancy. Small amounts of carbetocin has been shown to cross over from plasma into the breast milk of nursing women. The small amount of carbetocin ingested by infant would not be expected to present a significant safety concern.
Precaution:
Monitor BP in eclampsia and preeclampsia for up to 8 hrs. Inadequate uterine contraction (do not repeat treatment). Epilepsy; migraine; asthma.
Overdosage of carbetocin can be expected to produce enhanced pharmacological effects associated with uterine hyperactivity and pain. Treatment consists of symptomatic and supportive management.
Store at 2-8°C. Do not freeze. Keep away from light. Once the ampoule has been opened, the product should be used immediately.
Drugs acting on the Uterus
Carbetocin is a synthetic analogue of oxytocin reported to have a longer duration of action.
Use of carbetocin injection is contraindicated during pregnancy. Small amounts of carbetocin has been shown to cross over from plasma into the breast milk of nursing women. The small amount of carbetocin ingested by infant would not be expected to present a significant safety concern.
Samm Care