Anti-platelet drugs

By decreasing platelet aggregation, Aspirin inhibits thrombus formation on the arterial side of circulation, where thrombi are formed by platelet aggregation and anticoagulants have little effect. It is the analgesic of choice for headache, transient musculoskeletal pain, and dysmenorrhea. It has anti-inflammatory and antipyretic properties, which may be useful. Enteric coating reduces the intestinal disturbance and gastrointestinal ulceration due to this medicine.

Pain, Inflammatory diseases and as Antipyretic: Aspirin 300 mg 1-3 tablets 6 hourly with a maximum daily dose of 4 g.

Thrombotic cerebrovascular or Cardiovascular disease: Aspirin 300 mg 1 tablet or Aspirin 75 mg 4 tablets daily.

After Myocardial infarction: Aspirin 75 mg 2 tablets daily for 1 month.

Following By-pass surgery: Aspirin 75 mg 1 tablet daily.

Salicylates may enhance the effect of anticoagulants, oral hypoglycemic agents, phenytoin, and sodium valproate. They inhibit the uricosuric effect of probenecid and may increase the toxicity of sulfonamides. They may also precipitate bronchospasm or induce attacks of asthma in susceptible subjects.

Aspirin is contraindicated in children under 12 years of age (due to the risk of Reye's syndrome), during breastfeeding, and in cases of active peptic ulcer. It should also be avoided in conditions involving bleeding, such as hemophilia, intracranial hemorrhage, and other ulcerations.

Side effects for the typical dosage of Aspirin are generally mild and may include nausea, dyspepsia, gastrointestinal ulceration, and bronchospasm, among others.

It should be administered cautiously in cases of asthma, uncontrolled blood pressure, and during pregnancy.It should be administered with caution to patients with nasal polyps and nasal allergies.

Overdosage can result in symptoms such as dizziness, tinnitus, sweating, nausea, vomiting, confusion, and hyperventilation. Severe overdosage may lead to central nervous system depression with coma, cardiovascular collapse, and respiratory depression.

If an overdose is suspected, it is crucial to closely monitor the patient for at least 24 hours, as symptoms and salicylate blood levels may not become evident for several hours. The treatment for overdosage involves gastric lavage and forced alkaline diuresis. In severe cases, hemodialysis may be necessary.

Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.

Anti-platelet drugs

By reducing platelet aggregation, Aspirin inhibits thrombus formation on the arterial side of circulation, where thrombi primarily form through platelet aggregation, and anticoagulants have limited impact.

This medication is the preferred analgesic for addressing conditions such as headaches, transient musculoskeletal pain, and dysmenorrhea. It possesses anti-inflammatory and antipyretic properties, which can be beneficial. Enteric-coated Aspirin is effective in reducing intestinal disturbance and the risk of gastrointestinal ulceration due to its properties.

It is particularly crucial to avoid using aspirin during the final three months of pregnancy unless explicitly instructed by a physician, as it may lead to issues in the unborn child or complications during delivery.

Aspirin can enter breast milk, so it should be administered cautiously to nursing mothers.