Uses of Bexitrol: - Asthma - Chronic obstructive pulmonary disease (COPD) Chronic asthma, COPD Contraindicated in patients with hypersensitivity to Salmeterol or to the any excipient of this preparation. Monotherapy in the treatment of asthma. Treatment of status asthmaticus, other acute episodes of asthma or COPD.

How to use Salmeterol: Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Adult Dose: Inhalation Asthma Prevention and Maintenance, COPD Maintenance Adult: As inhaler: 2 puffs (50 mcg) twice daily; up to 100 mcg twice daily if needed. Prevention of Exercise-Induced Asthma 2 puffs (50 mcg) at least 30 min prior to exercise. Child Dose: Inhalation Child > 4 years Asthma Prevention and Maintenance, COPD Maintenance As inhaler: 2 puffs (50 mcg) twice daily; up to 100 mcg twice daily if needed. Prevention of Exercise-Induced Asthma 2 puffs (50 mcg) at least 30 min prior to exercise.

Diuretics, corticosteroids and xanthines may augment hypokalaemia. Risk of severe hypertension when used with MAOIs, TCAs and other sympathomimetics. Increased susceptibility to cardiac arrhythmias caused by digoxin and other cardiac glycosides.

Contraindicated in patients with hypersensitivity to Salmeterol or to the any excipient of this preparation. Monotherapy in the treatment of asthma. Treatment of status asthmaticus, other acute episodes of asthma or COPD.

Common - Tremor - Headache - Restlessness - Insomnia (difficulty in sleeping) - Palpitations - Muscle cramp >10% Headache (13-17%),Pain (1-12%) 1-10% Nasal congestion (9%),Hypertension (4%),Edema (1-3%),Dizziness (4%),Sleep disturbance (1-3%),Migraine (1-3%),Contact dermatitis (1-3%),Urticaria (3%),Hyperglycemia (1-3%),Articular rheumatism (1-3%),Paresthesia (1-3%),Muscular stiffness (1-3%),Photodermatitis (1-2%),Bronchitis (7%),Influenza (5%),Rigidity (1-3%),Rhinitis (5%),Asthma (3%) Frequency Not Defined Conjunctivitis,Hyperglycemia,Keratitis,Oral candidiasis,Chest tightness,Cataracts,Hypokalemia,Myositis

Precaution: Patient w/ CV disease, CNS disorders, DM, hyperthyroidism, hypokalaemia, seizure disorders, ketoacidosis. Not intended for the relief of acute bronchospasm. Hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor pulmonary function, BP, heart rate, CNS stimulation, hepatic function; glucose and K levels..

Salmeterol is a direct-acting sympathomimetic which relaxes bronchial smooth muscle by its selective action on beta 2 receptors with little effect on heart rate.