Uses of Anoxa: - Short term anxiety - Alcohol withdrawal Anxiety, Insomnia, Alcohol withdrawal syndrome Not for the treatment of psychoses. Pregnancy and lactation. Hypersensitivity, Acute alcohol intoxication, Myasthenia gravis (allowable in limited circumstances) Severe respiratory depression, Depressed neuroses.

How to use Oxazepam: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oxazepam may be taken with or without food, but it is better to take it at a fixed time. Administration: May be taken with or without food. Adult Dose: Oral Anxiety Mild/moderate: 10-15 mg 3-4 times/day. Severe, agitation or assoc with depression: 15-30 mg 3-4 times/day. Insomnia associated with anxiety Adult: 15-25 mg given 1 hr before bedtime. Alcohol withdrawal syndrome; Anxiety Adult: 15-30 mg 3 or 4 times daily. Elderly: Initially, 10 mg tid, increase up to 10-20 mg 3 or 4 times daily as necessary. Child Dose: Oral Anxiety Child >12 years Mild/moderate: 10-15 mg 3-4 times/day. Severe, agitation or assoc with depression: 15-30 mg 3-4 times/day. Renal Dose: Renal impairment: No dosage adjustment needed.

Additive CNS depressant effects w/ barbiturates, antipsychotics, sedatives/hypnotics, anxiolytics, antidepressants, sedative antihistamines, anticonvulsants, and anaesth. Increased psychic dependence w/ narcotic analgesics. CYP450 inhibitors may enhance benzodiazepine activity.

Not for the treatment of psychoses. Pregnancy and lactation. Hypersensitivity, Acute alcohol intoxication, Myasthenia gravis (allowable in limited circumstances) Severe respiratory depression, Depressed neuroses.

Common - Altered libido - Dizziness - Edema (swelling) - Lethargy - Nausea - Rash - Slurred speech - Tremor Sleep and visual disturbances, drowsiness, dizziness, vertigo, lethargy, headache, tremor, ataxia, mild paradoxical reactions (e.g. excitement, stimulation of affect), minor diffuse skin rashes (e.g. morbilliform, maculopapular and urticarial), nausea, oedema, slurred speech, altered libido, GI symptoms. Rarely, transient anterograde amnesia or memory impairment, syncope, leucopenia and hepatic dysfunction including jaundice.

Precaution: Patient w/ CV or cerebrovascular disease, acute narrow-angle glaucoma, suicidal tendencies, history of drug abuse or acute alcoholism, myasthenia gravis, chronic pulmonary insufficiency or sleep apnoea. Not intended for treatment of psychoses. Avoid abrupt withdrawal. Hepatic and renal impairment. Elderly or debilitated patient. Pregnancy and lactation. Patient Counselling May impair ability to perform hazardous activities requiring mental alertness or physical coordination (e.g. operating machinery, driving). Monitoring Parameters Monitor resp and CV status. Periodic monitoring of CBC and LFTs. Lactation: Avoid during breastfeeding

Store in a cool and dry place, protected from light and moisture. Keep out of reach of children.

Tricyclic Anti-depressant

Oxazepam is a short-acting benzodiazepine. It increases neuronal membrane permeability to Cl ions by binding to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron w/in the CNS (including the limbic system, reticular formation) and enhancing the GABA inhibitory effects resulting in hyperpolarisation and stabilisation.

This medication is not recommended for use during pregnancy due to the potential possible fetal harm. Based on information from related drugs, this drug may pass into breast milk and may have undesirable effects on a nursing infant. Therefore, breastfeeding while using this medication is not recommended.