This is indicated for the treatment and prevention of osteoporosis, osteomalacia, tetany, hypoparathyroidism & osteogenesis. It can be used as supplement in case of inadequate intake of Calcium in childhood diet, pregnancy & lactation, rickets & poor absorption during old age. Other indications include pancreatitis & phosphate binder in chonic renal failure etc.
Specific mineral & vitamin combined preparations
Calcium is absorbed in the intestine which than passed through the intestine to blood and deposited into bone. Active transport through cell is dependent on Vitamin D3. Vitamin D3 keeps bone healthy by increasing the absorption of calcium in the intestines. Without Vitamin D3 body will be able to absorb only 10% to 15% of the Calcium from the diet.
One tablet once or twice daily with plenty of water or food as directed by the physician.
Major interaction: Administering intravenous Ceftriaxone & Calcium can result in life-threatening damage to the lung & kidneys. Calcium should not be administered intravenously within 48 hours of intravenous.Minor interaction: Calcium can reduce the absorption of tetracycline & fluoride preparations and minimum 3 hours time should be allowed between ingestion of these medications. Thiazide diuretics reduce the renal excretion of calcium. Phenytoin, barbiturates & glucocorticoids may induce metabolism of Vitamin D3. Intake of certain foods like spinach, cereals, milk and its derivatives may reduce the intestinal uptake of calcium.
Increased activity of parathyroid gland, hypercalcemia, constipation, kidney stone & extreme loss of body water are such condition in which calcium intake is contraindicated.
Flatulance, diarrhoea, constipation and allergic reactions etc are rare manifestation. Hypercalcemia due to prolong use has rarely been reported.
This should be given to pregnant & lactating mothers as per recommendation of physician. Toxicity was tested on pregnant & lactating females which results excellent.
In mild hypercalciuria reduction of dose is sufficient to return to normal serum calcium concentration. Patients with kidney stone or with such previous history should be recommended to increase their fluid intake.
Store in a cool and dry place, protected from light.
