Aldocort 100 mcg
Fludrocortisone Acetate
Category: Tablet
Manufacturer: Incepta Pharmaceuticals Ltd.
Allopathic
MFG. Licence No. Biological
193
MFG. Licence No. Non-Biological
108
Address
Zirabo, Savar, Dhaka Dewan Idris Road, Bara Rangamatia
Price: 10.0 ৳
20 in Blister Pack
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Related Medicines
Uses of Aldocort:
- Addison's disease
- Congenital adrenal hyperplasia
Primary and secondary adrenocortical insufficiency in Addison disease, Salt-Losing Forms of Congenital Adrenogenital Syndrome
Hypersensitivity. Hyperalbuminaemia; hypertension, systemic fungal infections.
Corticosteroid
Fludrocortisone binds the mineralocorticoid receptor (aldosterone receptor). This binding (or activation of the mineralocorticoid receptor by fludrocortisone) in turn causes an increase in ion and water transport and thus raises extracellular fluid volume and blood pressure and lowers potassium levels.
How to use
Fludrocortisone Acetate:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
Fludrocortisone Acetate is to be taken with food.
Adult Dose:
Oral
Adult:
Primary adrenocortical insufficiency
Adrenocortical Insufficiency/Addison Disease
Primary and secondary adrenocortical insufficiency in Addison disease
Usual, 0.1 mg/day PO; range, 0.1 mg PO 3 times weekly to 0.2 mg/day PO
If hypertension occurs: 0.05 mg/day PO
Salt-Losing Forms of Congenital Adrenogenital Syndrome
0.1-0.2 mg/day PO
Child Dose:
Not FDA-approved for use in children
May decrease salicylate levels. Anticholinesterase effects are antagonised. Decreased effects with rifampin, barbiturates, hydantoins and phenytoin. Oral contraceptives or ritonavir may increase the plasma concentrations of fludrocortisone. Increased potassium loss with potassium-depleting drugs e.g. thiazides, furosemide or amphotericin B. Increased risk of GI bleeding or ulceration with NSAIDs. May alter efficacy of anticoagulants when used concurrently.
Hypersensitivity. Hyperalbuminaemia; hypertension, systemic fungal infections.
Common
- Behavioural changes
- Weight gain
- Bone disorder
- Thinning of skin
- Altered blood sugar level
- Mood changes
- Upset stomach
Acne, hypertension, sodium and water retention, potassium loss, dizziness, itching, skin rash, headache, convulsions, CHF, muscle weakness, hyperglycaemia, HPA and growth suppression, peptic ulcer, cataracts, raised intraocular pressure and reduced visual acuity. Insomnia, Menstrual irregularity, Myopathy, Neuritis, Osteoporosis
Pregnancy category C. There are no adequate and well-controlled studies in pregnant women. Fludrocortisone is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.Lactation: There are no data on the excretion of fludrocortisone into human milk. However, corticosteroids (systemic therapy) are distributed into breast milk and could cause growth suppression and/or other adverse effects in nursing infants. The manufacturer recommends that caution be used when administering Fludrocortisone to nursing women.
Precaution:
Use with caution in diabetes mellitus, hypertension, hypothyroidism, electrolyte abnormalities, sodium and water retention, infections, immunizations, ocular herpes simplex, myasthenia gravis, peptic ulcer disease, psychosis, renal insufficiency. Prolonged corticosteroid use may result in elevated intraocular pressure, glaucoma, or cataracts and has been associated with development of Kaposi sarcoma
Lactation: Unknown whether drug is excreted in milk; use with caution
Overdose is unlikely; however, treatment of overdose is by supportive and symptomatic therapy.
Store in a cool and dry place, protected from light.
Corticosteroid
Potent mineralocorticoid with high glucocorticoid activity; Fludrocortisone promotes increased reabsorption of sodium and excretion of potassium from renal distal tubules
Pregnancy category: C
Lactation: Unknown whether drug is excreted in milk; use with caution
Samm Care