Acicaft 0.25% Ophthalmic Solution

    Acicaft 0.25%

    Generic: Alcaftadine

    Category: Ophthalmic Solution

    Manufacturer: ACI Limited

    Price: 400.0

    5 ml drop

    Indications

    Uses of Acicaft: - Allergic eye disease Prevention of itching associated with allergic conjunctivitis. Acicaft eye drop is contraindicated in patients who are hypersensitive to any component of this product.

    Therapeutic Class

    Ophthalmic Anti-allergic preparations

    Pharmacology

    This eye drops is a sterile topical ophthalmic solution containing Alcaftadine. Alcaftadine is an histamine receptor antagonist and inhibitor of the release of histamine from mast cell. It is also a potent histamine H2 and H4 receptor antagonist that has demonstrated anti-inflammatory property. In doing so, antihistaminic effect provides relief from itching associated with early phase of ocular allergic response, whereas mast cell stabilization inhibits the release of mediators such as cytokines and lipid mediators that play a role in late-phase response of allergic conjunctivitis.

    Dosage and Administration

    How to use Alcaftadine: This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. Adult Dose: Instill one drop in each eye once daily.

    Interaction

    None well documented.

    Contraindications

    Alcaftadine eye drop is contraindicated in patients who are hypersensitive to any component of this product.

    Side Effects

    Common - Eye irritation - Itching - Stinging in the eyes - Burning eyes 1-10% Ocular Irritation,Burning,Stinging,Redness,Pruritus,Eye discharge,Eye swelling,Erythema of eyelid,Eyelid edema Nonocular Nasopharyngitis,Headache,Influenza,Somnolence

    Pregnancy And Lactation

    Pregnancy category B. There are however, no adequate and well controlled studies in pregnant women, thus this drug should be used during pregnancy only if clearly needed. It is not known whether this drug is excreted in human milk. Caution should be exercised while administered to a nursing woman.

    Precautions And Warnings

    Precaution: The drug should not be instilled while wearing contact lenses. If hypersensitivity reaction occurs after instillation patients should be advised to discontinue the use of Alcaftadine and consult with physicians. Lactation: Unknown whether distributed in breast milk, caution advised.

    Storage Conditions

    Store in a cool (15°C - 25°C) and dry place protected from light. Do not use after one month once the cap is opened.

    Drug Classes

    Ophthalmic Anti-allergic preparations

    Mode of Action

    Alcaftadine is an H1, H2 & H4 histamine receptor antagonist and inhibitor of the release of histamine from mast cells.

    Pregnancy Category

    Pregnancy Category: B Lactation: Unknown whether distributed in breast milk, caution advised
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